Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration
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Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration
We evaluated the pharmacokinetics of ciprofloxacin in serum (n = 6) and urine (n = 4) in goats following a single intravenous administration of 4 mg/kg body weight. The serum concentration-time curves of ciprofloxacin were best fitted by a two-compartment open model. The drug was detected in goat serum up to 12 h. The elimination rate constant (beta) and elimination half-life (t1/2beta) were 0....
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ژورنال
عنوان ژورنال: Journal of Veterinary Science
سال: 2008
ISSN: 1229-845X
DOI: 10.4142/jvs.2008.9.3.241